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Table 2 Grading of the certainty of evidence for recommendations

From: Brazilian recommendations for the management of tuberculosis infection in immune-mediated inflammatory diseases

Quality rating

Interpretation

High

Very confident that the true effect lies close to that of the estimate of the effect

Moderate

Moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect but there is a possibility that it is substantially different

Low

Our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect

Very low

Very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of the effect