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  1. Due to the rarity of relapsing polychondritis (RP), we described the demographic, clinical, treatment, outcomes, and comorbidities of patients with RP from our tertiary service. Additionally, a literature revi...

    Authors: Patricia Pilar Lury Ortale Ueda, Luiz Antonio Leandrini Komati and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2025 65:24
    Content type: Research Published on:

  2. Systemic sclerosis (SSc) is an autoimmune connective tissue disorder that can cause generalized inflammation and is characterized by fibrosis of the skin, organs, and vasculopathy. Limited SSc is more common a...

    Authors: Julia Jobanputra, Nikhil Furtado, Ali Bin Abdul Jabbar, Danielle B. Dilsaver, Noureen Asghar, Mohsin Mirza, Joseph Nahas and Abubakar Tauseef
    Citation: Advances in Rheumatology 2025 65:23
    Content type: Research Published on:

  3. The coexistence of dermatomyositis (DM)/clinically amyopathic DM (CADM) and psoriasis has been infrequently documented in the literature. Consequently, this study aimed to analyze this entity from our tertiary...

    Authors: Beatriz Westphalen Pomianoski and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2025 65:22
    Content type: Research Published on:

  4. To evaluate the effectiveness of intra-articular injections (IAIs) with triamcinolone hexacetonide (TH) combined with a progressive resistance exercise program (PREP) in improving pain, function, muscle streng...

    Authors: Christine Brumini, Rita Nely Vilar Furtado, Anamaria Jones, Raphael Vilela Timóteo da Silva and Jamil Natour
    Citation: Advances in Rheumatology 2025 65:21
    Content type: Research Published on:

  5. Fibromyalgia (FM) is a musculoskeletal syndrome characterized by diffuse and chronic pain associated with other symptoms such as fatigue, sleep/cognition disorders, headache, depression and anxiety, resulting ...

    Authors: Carolina Dias da Silva Amorim, Marco Felipe Macêdo Alves, Marcella Dias Teixeira, Larissa Vasconcelos Queiroz, Thaysa Walleria de Aragão Santos, Aline Ranzolin, Danyelly Bruneska Gondin Martins and Claudia Diniz Lopes Marques
    Citation: Advances in Rheumatology 2025 65:20
    Content type: Research Published on:

  7. The risk of tuberculosis infection (TBI) and its progression to tuberculosis disease (TBD) among persons with immune-mediated inflammatory diseases (IMID) results from a complex interplay of patient and diseas...

    Authors: Viviane Angelina de Souza, Ana Luiza Mendes Amorim Caparroz, Virginia Fernandes Moça Trevisani, Anna Carolina Faria Moreira Gomes Tavares, Ana Karla Guedes de Melo, Anete Trajman, Ana Cristina de Medeiros-Ribeiro, Marcelo de Medeiros Pinheiro, Ricardo Machado Xavier, Odirlei Andre Monticielo, Maria Fernanda Brandão de Resende Guimarães, Flavio Sztajnbok, Sidney Bombarda, Liliana Andrade Chebli, Adriana Maria Kakehasi, Ana Luiza Bierrenbach…
    Citation: Advances in Rheumatology 2025 65:18
    Content type: Guideline Published on:

  8. Apitoxin®, a drug based on bee venom was approved and released in Korea in 2003 as the ethical drug (ETC). It is well-known for its pain-relieving properties due to its potent anti-inflammatory effects. This rais...

    Authors: Duk-Yeon Cho, Young-Mo Kang and SangHo Seol
    Citation: Advances in Rheumatology 2025 65:17
    Content type: Research Published on:

  9. Numerous inflammatory complications related to COVID are described, including the Multisystem inflammatory Syndrome in Children (MIS-C) and Hyperinflammation. There is a scarcity of studies comparing these two...

    Authors: Ana Paula Radünz Vieira, Paulo Roberto Antonaccio Carvalho, Sandra Helena Machado and Taís Sica da Rocha
    Citation: Advances in Rheumatology 2025 65:16
    Content type: Research Published on:

  11. The recurrent nature and prolonged course of ankylosing spondylitis (AS) impose substantial psychological disorders on patients. The aim of this study was to assess psychological disorders and analyze the over...

    Authors: Kun Yang, Yifan Gong, Zhaoyang Geng, Xan Xu, Shiyan Yan, Haoran Zhang, Quan Jiang and Hongxiao Liu
    Citation: Advances in Rheumatology 2025 65:14
    Content type: Research Published on:

  12. In this interventional weight loss study, health-related quality of life (HRQoL), anxiety, depression and fatigue were compared at baseline (BL) and at 12 months (M12) in patients with psoriatic arthritis (PsA...

    Authors: Anton J. Landgren, Annelie Bilberg, Björn Eliasson, Linda Torres, Mats Dehlin, Lennart T. H. Jacobsson, Ingrid Larsson and Eva Klingberg
    Citation: Advances in Rheumatology 2025 65:13
    Content type: Research Published on:

  14. This double-blind, trial sought to assess the effectiveness of intra-articular ozone therapy at concentrations of 20 µg/mL and 40 µg/mL in managing pain and enhancing functional mobility in patients with knee ...

    Authors: Zahra Arjmanddoust, Ahmad Nazari and Azar Moezy
    Citation: Advances in Rheumatology 2025 65:11
    Content type: Research Published on:

  15. The overlap of non-cirrhotic idiopathic portal hypertension (NCIPH) and systemic sclerosis (SSc) is rare. This article reports one case of a patient with SSc developing NCIPH and presents a systematic review o...

    Authors: Felipe Souza da Silva, João Victor de Pinho Costa, Carlos Alberto dos Santos Júnior, Érika Emmylaine dos Santos, Ailton José de Castro Júnior, Ana Cecília de Sena Oliveira, Flávia Patrícia Sena Teixeira Santos, Adriana Maria Kakehasi and Débora Cerqueira Calderaro
    Citation: Advances in Rheumatology 2025 65:10
    Content type: Review Published on:

  16. Anti-PM/Scl autoantibody has been associated with an overlap between polymyositis (PM) and systemic sclerosis (SSc). However, due to limited studies, the relevance of this autoantibody in patients with idiopat...

    Authors: Rafaella do Amaral Barbosa and Samuel Katsuyuki Shinjo
    Citation: Advances in Rheumatology 2025 65:9
    Content type: Research Published on:

  17. There is no consensus on the classification of lupus arthritis (LA). In this study, we aimed to investigate patients with LA who were clinically and serologically very similar to those patients with rheumatoid...

    Authors: Mete Pekdiker and Mete Kara
    Citation: Advances in Rheumatology 2025 65:8
    Content type: Research Published on:

  18. Neurological and psychiatric manifestations occur in patients with primary Sjogren’s disease (SjD) with a wide-ranging clinical presentation, affecting quality of life, social participation, and prognosis. Des...

    Authors: Fabiola Reis de Oliveira, Simone Appenzeller, Sandra Gofinet Pasoto, Marilena Leal Mesquita Silvestre Fernandes, Maria Lucia Lemos Lopes, Sonia Cristina de Magalhães Souza Fialho, Aysa Cesar Pinheiro, Laura Caldas dos Santos, Valeria Valim, Erica Vieira Serrano, Sandra Lucia Euzébio Ribeiro, Tatiana Nayara Libório‑Kimura, Danielle Christinne Soares do Egypto, Diego Ustárroz Cantali, Juliana D’Agostino Gennari, Samira Tatiyama Miyamoto…
    Citation: Advances in Rheumatology 2025 65:7
    Content type: Position Statement Published on:

  19. To date, there has been limited exploration, particularly on a national scale, of the prevalence patterns of comorbidities and complications associated with rheumatoid arthritis (RA) in Colombia. We aimed to a...

    Authors: Kevin Maldonado-Cañón, Giancarlo Buitrago and Gerardo Quintana-López
    Citation: Advances in Rheumatology 2025 65:6
    Content type: Research Published on:

  20. The clinical manifestations and course of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) exhibits considerable heterogeneity. In this study, we aimed to explore radiographic progression ove...

    Authors: Duygu Temiz Karadag, Sevtap Dogan, Neslihan Gokcen, Oznur Sadioglu Cagdas, Ayten Yazici and Ayse Cefle
    Citation: Advances in Rheumatology 2025 65:5
    Content type: Research Published on:

  21. To compare the impact of COVID-19 on the clinical status and psychological distress of patients with immune-mediated rheumatic disease (IMRD) caused by SARS-CoV-2 infection with that of noninfected IMRD contro...

    Authors: Claudia Marques, Marcelo M. Pinheiro, Jennifer Lopes, Sandra Lúcia Euzébio Ribeiro, Mary Vânia Marinho de Castro, Lilian David de Azevedo Valadares, Aline Ranzolin, Nicole Pamplona Bueno de Andrade, Rafaela Cavalheiro do Espírito Santo, Nafice Costa Araújo, Cintya Martins Vieira, Valéria Valim, Flavia Patricia Sena Teixeira Santos, Laurindo Ferreira da Rocha Jr., Adriana Maria Kakehasi, Ana Paula Monteiro Gomides Reis…
    Citation: Advances in Rheumatology 2025 65:4
    Content type: Research Published on:

  22. Authors: Graziela Vieira Cavalcanti, Fabiola Reis de Oliveira, Rafael Ferraz Bannitz, Natalia Aparecida de Paula, Ana Carolina Fragoso Motta, Eduardo Melani Rocha, John Chiorini, Hilton Marcos Alves Ricz, Denny Marcos Garcia, Maria Cristina Foss-Freitas and Luiz Carlos Conti de Freitas
    Citation: Advances in Rheumatology 2025 65:3
    Content type: Correction Published on:

    The original article was published in Advances in Rheumatology 2025 65:2

  23. Endoplasmic reticulum stress (ERS) and the unfolded protein response (UPR) are adaptive mechanisms for conditions of high protein demand, marked by an accumulation of misfolded proteins in the endoplasmic reti...

    Authors: Graziela Vieira Cavalcanti, Fabiola Reis de Oliveira, Rafael Ferraz Bannitz, Natalia Aparecida de Paula, Ana Carolina Fragoso Motta, Eduardo Melani Rocha, John Chiorini, Hilton Marcos Alves Ricz, Denny Marcos Garcia, Maria Cristina Foss-Freitas and Luiz Carlos Conti de Freitas
    Citation: Advances in Rheumatology 2025 65:2
    Content type: Research Published on:

    The Correction to this article has been published in Advances in Rheumatology 2025 65:3

  24. Transition clinics are conceived as programs dedicated to the active, multidimensional development of a process that addresses the medical, psychosocial, educational, and vocational needs of pediatric patients...

    Authors: Lauren Natalia Ramirez, María Elisa Hoyos, Angela Catalina Mosquera-Pongutá and Gerardo Quintana-López
    Citation: Advances in Rheumatology 2025 65:1
    Content type: Review Published on:

  25. Osteoarthritis (OA) is a common degenerative joint disease. Circular RNA Phosphodiesterase 1 C (circ-PDE1C, hsa_circ_0134111) has participated in the IL-1β-induced chondrocyte damages. The objective of our stu...

    Authors: Lixia Gao, Tao He, Qingkui Hu and Yan Ma
    Citation: Advances in Rheumatology 2024 64:92
    Content type: Research Published on:

  26. As a master immune system regulator, transforming growth factor β1 (TGF-β1) is closely linked to the complicated pathophysiology and development of systemic sclerosis (SSc), a multisystem fibrotic disease.

    Authors: Sakeena Ayub, Tabasum Shafi, Roohi Rasool, Mushtaq A. Dangroo, Muzaffar A. Bindroo, Ayaz Gull, Lamya Ahmad Al-Keridis, Nawaf Alshammari, Mohd Saeed and Zafar Amin Shah
    Citation: Advances in Rheumatology 2024 64:91
    Content type: Research Published on:

  27. The prevalence of Fibromyalgia in patients with Systemic Lupus Erythematosus (SLE) is significantly higher compared to the general population. Despite this frequent association, Fibromyalgia remains underdiagn...

    Authors: Jade A. M. Monteiro, Alexia L. H. Gama, Joao C. S. Oliveira, Matheus V. Falcao, Ana Karla G. Melo, Danielle C. S. Egypto and Alessandra S. Braz
    Citation: Advances in Rheumatology 2024 64:90
    Content type: Research Published on:

  28. Despite previous studies indicating a close relationship between immune system and ankylosing spondylitis (AS), the causal relationship between them remains unclear.

    Authors: Ziming Geng, Yang Tong, Yang Chen, Jian Wang, Ziwen Liu, Jun Miao and Ruihua Li
    Citation: Advances in Rheumatology 2024 64:89
    Content type: Research Published on:

  29. We investigated role of haematopoietic cell kinase (Hck) in osteoarthritis (OA) and to explore the underlying mechanisms driving its effects. An OA animal model was established and after OA induction, rats rec...

    Authors: Zhenzhong Yan and Lin Ji
    Citation: Advances in Rheumatology 2024 64:88
    Content type: Research Published on:

  30. Describe tofacitinib safety from an integrated analysis of randomized controlled trials (RCTs) in patients with ankylosing spondylitis (AS).

    Authors: Atul Deodhar, Servet Akar, Jeffrey R. Curtis, Bassel El-Zorkany, Marina Magrey, Cunshan Wang, Joseph Wu, Solomon B. Makgoeng, Ivana Vranic, Sujatha Menon, Dona L. Fleishaker, Annette M. Diehl, Lara Fallon, Arne Yndestad and Robert B. M. Landewé
    Citation: Advances in Rheumatology 2024 64:87
    Content type: Research Published on:

  32. Sarcopenia is a muscle disease characterized by reduction of muscle strength and muscle mass. In RA, 25.9 to 43.3% of the patients present sarcopenia. The loss of muscle mass observed in RA patients occurs eit...

    Authors: Thales Hein da Rosa, Bárbara Jonson Bartikoski, Rafaela Cavalheiro do Espírito Santo, Mirian Farinon, Jordana Miranda de Souza Silva, Renata Ternus Pedó, Maria Luísa Gasparini, Thais Karnopp, Leonardo Peterson dos Santos, Gustavo Chapacais, Andressa di Domenico, Sofia Loch and Ricardo Machado Xavier
    Citation: Advances in Rheumatology 2024 64:85
    Content type: Research Published on:

  33. Takayasu arteritis (TA) and tuberculosis (TB) share similar histopathological and immunological characteristics. Studies comparing patients with TA with or without active or latent TB infection (LTBI) have rev...

    Authors: Ana Luisa Souza Pedreira, Maria de Lourdes Castro de Oliveira Figueiroa, Mariana Oliveira Miranda, Alisson Regis de Santana, Victor Pereira Mattos, Adriane Sousa da Paz, Camila Cendon Duran and Mittermayer Barreto Santiago
    Citation: Advances in Rheumatology 2024 64:84
    Content type: Research Published on:

  34. Immune factors are crucial in the pathogenesis of rheumatoid arthritis (RA), and immune cells play a key role in the development of RA. However, there is still disagreement regarding the specific roles of each...

    Authors: Feng Cheng, YingJia Zhu, XiaoQian Liu, RuiKun Zhang, Fei Xia and LinPu Ge
    Citation: Advances in Rheumatology 2024 64:83
    Content type: Review Published on:

  35. Authors: Edgard Torres dos Reis-Neto, Luciana Parente Costa Seguro, Emília Inoue Sato, Eduardo Ferreira Borba, Evandro Mendes Klumb, Lilian Tereza Lavras Costallat, Marta Maria das Chagas Medeiros, Eloisa Bonfá, Nafice Costa Araújo, Simone Appenzeller, Ana Carolina de Oliveira e Silva Montandon, Emily Figueiredo Neves Yuki, Roberto Cordeiro de Andrade Teixeira, Rosa Weiss Telles, Danielle Christinne Soares do Egypto, Francinne Machado Ribeiro…
    Citation: Advances in Rheumatology 2024 64:82
    Content type: Correction Published on:

    The original article was published in Advances in Rheumatology 2024 64:48

  36. Fibromyalgia is a non-inflammatory syndrome characterized by generalized muscle pain, with other symptoms. Numerous forms of physical training for this population have been studied through high-quality randomi...

    Authors: Giovana Fernandes, Michele Nery, Sandra Mara Meireles, Rebeka Santos, Jamil Natour and Fabio Jennings
    Citation: Advances in Rheumatology 2024 64:81
    Content type: Research Published on:

  37. Today, the prescription of tramadol in patients with osteoarthritis (OA) has increased significantly, which can be associated with serious consequences. Contradictory results have been reported regarding the a...

    Authors: Mansour Bahardoust, Sepideh Mousavi, Maryam Zolfaghari Dehkharghani, Mahsa Arab, Heeva Rashidi, Habib Gorgani, Meisam Haghmoradi and Alireza Askari
    Citation: Advances in Rheumatology 2024 64:80
    Content type: Review Published on:

  38. Systemic vasculitis is a group of rare diseases that share an essential characteristic: inflammation of blood vessel walls. This injury occurs during the disease course, but specific features vary for each ent...

    Authors: Joao Gabriel Dantas, Erika Biegelmeyer, Eduarda Bonelli Zarur and Frederico Augusto Gurgel Pinheiro
    Citation: Advances in Rheumatology 2024 64:79
    Content type: Review Published on:

  39. SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political. Most of the available information comes from the United States, Euro...

    Authors: Marco Ulises Martinez-Martinez, Carolina Ayelen Isnardi, Deshiré Alpizar-Rodriguez, Guillermo Javier Pons-Estel, Belén María Virasoro, María Agustina Alfaro, Ingrid Petkovic, Rosana Quintana, Guillermo Berbotto, María Jezabel Haye Salinas, Sofía Ornella, Mariana Pera, Iris Jazmín Colunga-Pedraza, Fedra Irazoque-Palazuelos, Greta Reyes-Cordero, Tatiana S Rodriguez-Reyna…
    Citation: Advances in Rheumatology 2024 64:78
    Content type: Research Published on:

  40. Hand osteoarthritis (HOA) is a highly prevalent disease that may be impacted by social inequalities. Few studies in HOA are from underdeveloped regions. We intend to contribute to fill this gap presenting clin...

    Authors: Francisco Vileimar Andrade de Azevedo, João Pedro Sobreira Borges, Antonio Matos de Souza Filho, José Carlos Godeiro Costa Junior, Cláudio Régis Sampaio Silveira and Francisco Airton Castro Rocha
    Citation: Advances in Rheumatology 2024 64:77
    Content type: Research Published on:

  42. Psoriatic arthritis can involve several domains. Due to its multifaceted nature and its frequent comorbidities such as depression, obesity, osteoarthritis and fibromyalgia, it is difficult to monitor these pat...

    Authors: Andrieli Caroline Mehl, Leonardo Michaelis Schmidt and Valderílio Feijó Azevedo
    Citation: Advances in Rheumatology 2024 64:75
    Content type: Research Published on:

  43. Although the terms “rare diseases” (RD) and “orphan diseases” (OD) are often used interchangeably, specific nuances in definitions should be noted to avoid misconception. RD are characterized by a low prevalen...

    Authors: Renan Rodrigues Neves Ribeiro do Nascimento, Daniela Gerent Petry Piotto, Eutilia Andrade Medeiros Freire, Fabricio de Souza Neves, Flavio Roberto Sztajnbok, Blanca Elena Rios Gomes Bica, Frederico Augusto Gurgel Pinheiro, Katia Tomie Kozu, Ivanio Alves Pereira, Valderilio Feijo Azevedo, Rafael Alves Cordeiro, Henrique Ayres Mayrink Giardini, Marco Túlio Muniz Franco, Margarida de Fátima Fernandes Carvalho, Nilton Salles Rosa-Neto and Sandro Félix Perazzio
    Citation: Advances in Rheumatology 2024 64:74
    Content type: Review Published on:

  45. Limited data exist on psoriatic arthritis (PsA) treatment in lower-income regions, particularly from the patient perspective. This study explores the challenges faced by socioeconomically vulnerable PsA patien...

    Authors: André Lucas Ribeiro, Júlia Andressa Tessari, Charles Lubianca Kohem, Penélope Esther Palominos and Rafael Mendonça da Silva Chakr
    Citation: Advances in Rheumatology 2024 64:72
    Content type: Research Published on:

  46. Amyloidosis is a localized or systemic disease caused by deposition of proteins in the extracellular space of various organs and tissues. As part of the disease, proteins that were originally soluble misfold a...

    Authors: Ivanio Alves Pereira, Nilton Salles Rosa Neto, Renan Rodrigues Neves Ribeiro do Nascimento, Eutilia Andrade Medeiros Freire, Fabricio de Souza Neves, Blanca Elena Rios Gomes Bica, Frederico Augusto Gurgel Pinheiro, Sandro Félix Perazzio, Rafael Alves Cordeiro, Henrique Ayres Mayrink Giardini, Valderilio Feijo Azevedo and Flavio Roberto Sztajnbok
    Citation: Advances in Rheumatology 2024 64:71
    Content type: Review Published on:

  47. To evaluate the tuberculin skin test (TST) conversion in chronic inflammatory arthropathies (CIA) patients on TNFα inhibitors (TNFi) and without previous latent tuberculosis infection (LTBI) treatment.

    Authors: Vanessa de Oliveira Magalhães, Karina Rossi Bonfiglioli, Carina More Frade Gomes, Eloisa Bonfá, Ana Cristina de Medeiros-Ribeiro, Carla Gonçalves S. Saad and Marcelo de Medeiros Pinheiro
    Citation: Advances in Rheumatology 2024 64:70
    Content type: Research Published on:

  48. Ankylosing spondylitis (AS) has been known to have auto-inflammatory nature; hence, the efficacy of autoantibodies is low. However, studies on autoantibodies are ongoing, with some studies showing associations...

    Authors: Yeo-Jin Lee, Eun-Ju Lee, Soo Min Ahn, Seokchan Hong, Ji Seon Oh, Chang-Keun Lee, Bin Yoo and Yong-Gil Kim
    Citation: Advances in Rheumatology 2024 64:69
    Content type: Research Published on:

  49. Spondyloarthritis (SpA) encompasses a spectrum of immune-mediated inflammatory conditions primarily affecting the axial skeleton, including sacroiliitis and spondylitis, each with distinct features. This study...

    Authors: Gabriel Caetano Pereira, Natalia Pereira Machado, André Francisco Gomes, Rodrigo Luppino Assad, Fabio Henrique Carneiro and Valderílio Feijó Azevedo
    Citation: Advances in Rheumatology 2024 64:68
    Content type: Research Published on:

  50. Progranulin (PGRN) is a growth factor-like molecule with diverse roles in homeostatic and pathogenic processes including the control of immune and inflammatory responses. Pathogenic inflammation is a hallmark ...

    Authors: Michun He, Aubryanna Hettinghouse, Yufei Bi, Yuehong Chen and Chuanju Liu
    Citation: Advances in Rheumatology 2024 64:67
    Content type: Research Published on:
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  • Citation Impact 2023
    Journal Impact Factor: 2.0
    5-year Journal Impact Factor: 2.6
    Source Normalized Impact per Paper (SNIP): 0.810
    SCImago Journal Rank (SJR): 0.704

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Advances in Rheumatology

ISSN: 2523-3106