Fig. 4

Tofacitinib treatment increases protein levels of myogenin in TA muscle without changes in Myod and Pax7 content. Protein expression of regeneration markers in TA muscle A PAX7, B Myod, C Myogenin, and D MuRF-1 with the representative western blot bands. Statistical analysis between groups was performed using ANOVA one-way followed by Tukey’s test. Data are represented as mean ± standard error of the mean (SEM). *p < 0.05. Control group n = 3; Vehicle group n = 3; Tofacitinib group n = 3