Fig. 6

Effect of the PD-1/PD-L1 signaling axis on the secretion of cytokines IFN-γ and IL-10 in the CD4⁺T/CD19⁺BCs co-culture system. (A-B) CD19⁺BCs and CD4⁺TCs isolated from PBMC of HC and SLE patients were co-cultured with anti-PD-L1 or isotype antibodies and IFN-γ (A) and IL-10 (B) were quantified 72 h later by ELISA. *P < 0.05