Fig. 3

Effect of activated CD19+BCs on the expression and proliferation of PD-L1 and PD-1 in CD4+TCs. (A) Representative histograms of PD-L1 expression on total CD19+BCs. (B) Expression (frequency, left panel, and MFI, right panel) of CD19+PD-L1+BCs. (C) Flow cytometry of the effects of activated CD19+BCs on the proliferation of CD4+TCs, and statistical results of the effects of activated CD19+BCs on the proliferation of CD4+TCs (D) and the expression of PD-L1 (E) and PD-1 (F). *P < 0.05, **P < 0.01, ***P < 0.001