| | Femoral cartilage | Tibial cartilage |
|---|
Sham | ACLT | Meniscotomy | Sham | ACLT | Meniscotomy |
|---|
3 days | 0 (0–1) | 1 (0–2) | 1 (0–2) | 0 (0–1) | 1 (0–2) | 1 (0–2) |
7 days | 0 (0–1) | 1 (0–2) | 1 (0–2) | 1 (0–1) | 1 (0–2) | 1 (0–3) |
14 days | 0 (0–1) | 0 (0–2) | 1 (1–2) | 1 (0–1) | 1 (0–3) | 1 (1–3) |
- Three groups of mice were subjected to a sham procedure, transection of both the knee collateral and anterior cruciate ligaments (ACLT) or ACLT followed by transection of the medial meniscus (MNCT) and sacrificed at various days postsurgery. Structural damage of the cartlage in the distal femur and tibial plateau was evaluated using OM, according to previous criteria (see text for details). Data represent medians (range) of n = 4 animals/group; difference between medians assessed using Kruskal–Wallys test
